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Always love the podcast, and this format is lovely! Please keep up the good work, I hope more trainees and practicing psychiatrists check you guys out. (and love the collab between Carlet and PsychoFarm!)

reducing/eliminating risk of drug-induced movement disorders can be viewed as game changing

Sounds like it could be a good tool, BID dosing with schizophrenics patients does sound daunting though

Links mentioned in the video: ADHD Webinars: www.thecarlatreport.com/blogs/3-carlat-psychiatry-webinars/post/4198-how-to-select-a-stimulant-formulation www.thecarlatreport.com/blogs/3-carlat-psychiatry-webinars/post/4197-amphetamine-vs-methylphenidate The Benzodiazepine-Stimulant Combo: What Could Go Wrong?: www.thecarlatreport.com/articles/4105-the-benzodiazepine-stimulant-combo-what-could-go-wrong Psychopharm Commandment 5: Benzos Opioids: www.thecarlatreport.com/blogs/2-the-carlat-psychiatry-podcast/post/4249-psychopharm-commandment-5-benzos-opioids

Great video! Would you mind sharing the links you mentioned at the end? The second link in the description directs to an error page FYI. Thank you!

There is one glaringly misleading/inacurate statement in this video: that any individual response to a high dose of an antidepressant is attributable to placebo. You might find in a large population that the average response to a high dose antidepressant is not significantly different than to a low dose. This DOES NOT mean that NO individuals have a differential response to high vs low dose! It means that those folks are in the minority. Thus, for a patient not responding to a low dose antidepressant, without any tolerability issues, it is absolutely worth trying dose escalation, as tolerated.

This pubmed.ncbi.nlm.nih.gov/18830236/ was the best designed study that addressed this question and the results were clearly negative

Loving the content, per usual!

Helpful and educational, as always!

Thanks for the video. In the diagnosis of ADHD, one problem is that the criteria used in the some diagnostic manuals unfortunately describe signs as "symptoms". Medically, symptoms are subjective, whereas signs are objective or can be seen from the "outside". Also, many key aspects of ADHD, such as emotional dysregulation, are not even given attention (no pun intended) in the DSM-V, etc. But these are, in fact, true symptoms, and they can't always be observed by an outsider; the doctor has to take the patient at their word e.g. "I am experiencing a deep feeling of rejection because of what somebody just said to me before this appointment. Now my emotions are all over the place". I think the diagnostic manuals today are mostly aimed at diagnosing children, not adults. You aren't going to see many adults jumping on top of tables during a work meeting. Instead, the hyperactivity is usually more of an inward experience. It's sad that the main diagnostic manuals are so aloof as to how ADHD truly manifests in real life.

Cobenfy tablet When will come in India sir

Beautiful video!

I shall always like your videos. It is exciting to have a newer mechanism of action in the market but I am hesitant to prescribe it until we have independent RTCs

great video! thank you for this!

Great video! Easy to understand and informative.

What if Wellbutrin never worked for me in the past? I took it for 6 months and it did nothing. Actually, everything I had taken didn’t work for me. I did take one of those DNA Geomimd test.

It’s great hearing a credible & refreshing source on this topic !

Thank you so much for including the cultural history and resulting policy decisions, admitting to bias in prescribing practices tells me how very thoughtful your conclusions and recommendations are, simply a fantastic presentation here for the layperson to understand better, and thereby give better feedback to care providers. I’ll surely tax the patience of my psychiatrist, I refuse the phoning it in approach to medical practice as I suffered a psychotic break from a wrong mix. I simply need to fully understand, or I’m not putting it in my body. Kindest regards doc, you’re awesome.

Is it weight gaining or causes constipation.plz confirm this .

I'm interested in the follow up video you mentioned

What about when they are used together? The is one particular psychiatrist that gives Guanfacine ER in AM and clonidine IR at HS.

Excellent ❤❤❤

💡Fact Sheet: www.thecarlatreport.com/alpha2 📖Medication Fact Book: www.thecarlatreport.com/products/499-medication-fact-book-for-psychiatric-practice-seventh-edition-2024

Great video 👍

Doctor gave me this today for anxiety. Should I not take this?

I’m surprised anyone prescribes BuSpar. I’ve had maybe one patient tell me it helps them, the rest didn’t think so. I took it when it was brand new and I couldn’t remember anything from the previous day. 😬

Is this a joke? No advantages in efficacy. You get nothing for combining it with other agents, so useless for augmentation. _And_ it causes QT prolongation? Ain't nothin' cute about that! Why would you ever prescribe or take it? There are older drugs that are safe and effective. If you've literally tried everything, gone through SSRI's, SNRI's, atypical antidepressants, tricyclics, MAOI's... You still have better options than Gepirone.

Congratulations for the Excellent work!

Am I dumb? Don't NMDA antagonists decrease glutamate transmission?

hey really nice video i was wandering if i could help you edit highly engaging videos

I'm so glad i discovered this

So practical and helpful! Really appreciate this concise summary.

Hydrate....Hydrate....HYDRATE

Let us know in the comments what content you'd like to see in future videos-we're always open to your feedback and suggestions! 💡Stimulant Max Dose Table: www.thecarlatreport.com/stimulantlimits 📖Medication Fact Book: www.thecarlatreport.com/products/category/107-books/product/498-regular-bound-with-pdf-ebook-access

I enjoy this method of delivery very much. This form of media is easy to digest and I can easily tune in during morning commute. It reminds me of Dnews from nearly a decade ago. If you are guys are open for feedback, I have some suggestions. Better advertise this TH-cam channel on your website. I'm confident there is a demand for this content. Clinicians may just not be aware it exists. List all sources in the video description. I appreciated how screenshots were shared on screen but a link is always classy.

There is other support in the literature for the anti-depressant/mania thing but it is usually ignored in discussions and reviews

Methylphenidate sucks and those stealing the amphetamines should be forced to eat Methylphenidate on a daily basis. It causes serotonin syndrome.

Best video yet!

th-cam.com/video/W8r-tXRLazs/w-d-xo.html

I would love for there to be an affective at home opition for ketamine. I provide esketamine therapy for my patients, but obtaining it for them can be difficult and delays treatment. The specialized pharmacy it ships from often arranges delivery with the patient not me so it is sent back because I am not there to sign for it, and I have had insurance companies only give me a PA for 2 weeks at a time. I find the data on Rexulti interesting, but I have never seen an insurance company that will cover it, unless another AP has been tried first due to the cost.

Why is there no mention of the NYT exposé confirming that Acadia violated patients rights by holding them for insurance money?

great edition! thank you!

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This looks biased. Where are the studies ?

Only here for Dr Malzberg!

So many programs out there that promise you'll quit drinking from one day to the next and feel great for the rest of your life. Listen, Steffon Barkload's Quit Drinking Forever takes a lighter, safer approach which you decide to go with at your own pace. Best shortcut I go’ogled that only took days to rewire my brain to continually experience mental peace.

What about folinic acid?

Great video!! So helpful, as always. Look forward to seeing more!

Thank you for this - is there any similar research for bipolar (i.e., for hypomania)?