- 212
- 83 575
Open Box Science
United States
เข้าร่วมเมื่อ 8 ก.ค. 2020
Open Box Science makes science talks OPEN for the world.
[Katie Houlahan] Germline-mediated immunoediting sculpts breast cancer subtypes and metastasis
[Katie Houlahan] Germline-mediated immunoediting sculpts breast cancer subtypes and metastasis
Link to paper: www.science.org/doi/10.1126/science.adh8697
Link to paper: www.science.org/doi/10.1126/science.adh8697
มุมมอง: 36
วีดีโอ
[Ankit Malik] IFNγ signalling and compartmentalized antigen presentation orchestrate gut immunity
มุมมอง 4616 ชั่วโมงที่ผ่านมา
[Ankit Malik ] The University of Chicago Pritzker School of Medicine Epithelial IFNγ signalling and compartmentalized antigen presentation orchestrate gut immunity
[Kentaro Yomogida] The transcription factor Aiolos restrains the activation of intestinal...
มุมมอง 5016 ชั่วโมงที่ผ่านมา
Kentaro Yomogida - University of Colorado - The transcription factor Aiolos restrains the activation of intestinal intraepithelial lymphocytes
[Orian Bricard] The tissue-resident regulatory T cell pool is shaped by transient multi-tissue.....
มุมมอง 4216 ชั่วโมงที่ผ่านมา
The tissue-resident regulatory T cell pool is shaped by transient multi-tissue migration and a conserved residency program (Immunity 2024)
[Silvia Galván-Peña] A dynamic atlas of immunocyte migration from the gut
มุมมอง 33วันที่ผ่านมา
A dynamic atlas of immunocyte migration from the gut (Science Immunology 2024) (Harvard Medical School)
[Piotr Konieczny] Metabolic coordination between skin epithelium and type 17 immunity sustains...
มุมมอง 122หลายเดือนก่อน
Speaker: Dr. Piotr Konieczny NYU Langone Health Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation (Immunity 2024)
[Jimmy Zhang] ML Identify Predictive Features of Patient Mortality across Dementia
มุมมอง 56หลายเดือนก่อน
[Jimmy Zhang] ML identify predictive features of patient mortality across dementia types Paper link: www.nature.com/articles/s43856-024-00437-7
[Noa Rachmian] Identification of senescent, TREM2-expressing microglia in aging & AD mouse brain
มุมมอง 2682 หลายเดือนก่อน
Noa Rachmian (Weizmann Institute of Science) Identification of senescent, TREM2-expressing microglia in aging and Alzheimer’s disease model mouse brain
[ Alex Chen ] The aged tumor microenvironment limits T cell control of cancer
มุมมอง 1762 หลายเดือนก่อน
[ Alex Chen ] The aged tumor microenvironment limits T cell control of cancer Massachusetts General Hospital - Harvard Medical School
[Sarah Maritan and Miranda Yu] Spatial immune landscapes of primary and metastatic brain tumours
มุมมอง 1634 หลายเดือนก่อน
Miranda Yu (McGill University) and Sarah Maritan (Goodman Cancer Institute, McGill University) “Single-cell spatial immune landscapes of primary and metastatic brain tumours” (Nature 2023) Moderator: Michael Schulz (Georg-Speyer-Haus)
[Priya Devarajan] How are lung cytotoxic CD4 effectors generated during infection?
มุมมอง 2945 หลายเดือนก่อน
Speaker: Dr Priya Devarajan (Department of Pathology, University of Massachusetts Chan Medical School, Worcester, MA, USA) Paper highlighted: Cytotoxic CD4 development requires CD4 effectors to concurrently recognize local antigen and encounter type I IFN-induced IL-15 (www.cell.com/cell-reports/fulltext/S2211-1247(23)01194-4)
[Nadezhda Terekhanova] Epigenetic regulation during cancer transitions across 11 tumour types
มุมมอง 2886 หลายเดือนก่อน
[Nadezhda Terekhanova] Epigenetic regulation during cancer transitions across 11 tumour types Original paper: www.nature.com/articles/s41586-023-06682-5 #cancerresearch #singlecell #genomics
[Alon Millet] An exhausted-like microglial population accumulates in aged & APOE4 genotype AD brains
มุมมอง 3857 หลายเดือนก่อน
Alon Millet (Rockefeller Univ.) "An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains (Immunity 2023)"
[Wei Su] CD8 T cells: friend or foe in neurodegeneration
มุมมอง 2667 หลายเดือนก่อน
Wei Su (St. Jude Children's Research Hospital; current: Stanford University) "CD8 T cells: friend or foe in neurodegeneration" Ref: CXCR6 orchestrates brain CD8 T cell residency and limits mouse Alzheimer's disease pathology (Nat Immunol 2023)
[Nicoletta Caronni] IL1beta+ macrophages fuel pathogenic inflammation in pancreatic cancer
มุมมอง 3538 หลายเดือนก่อน
Speaker: Nicoletta Caronni (Ospedale San Raffaele, Milan, Italy) Paper: IL1beta macrophages fuel pathogenic inflammation in pancreatic cancer (Nature, 2023) Moderator: Anna Salamero Boix (Georg-Speyer-Haus)
[Bernhard Sabel] Mass Production of Fake Science Publishing: How Big is the Problem and Why?
มุมมอง 14210 หลายเดือนก่อน
[Bernhard Sabel] Mass Production of Fake Science Publishing: How Big is the Problem and Why?
[Meghan Laturney] How the neuroendocrine circuit that regulates sugar feeding in mated females
มุมมอง 11810 หลายเดือนก่อน
[Meghan Laturney] How the neuroendocrine circuit that regulates sugar feeding in mated females
[Dana Galili] Parallel representations of position and identity in the olfactory system
มุมมอง 8710 หลายเดือนก่อน
[Dana Galili] Parallel representations of position and identity in the olfactory system
[Fran Martínez Jiménez] Unraveling the immunogenics determinants of metastasis across human cancers
มุมมอง 21311 หลายเดือนก่อน
[Fran Martínez Jiménez] Unraveling the immunogenics determinants of metastasis across human cancers
[Nathaniel D. Bachtel] Immune sensing of food allergens promotes avoidance behavior
มุมมอง 32911 หลายเดือนก่อน
[Nathaniel D. Bachtel] Immune sensing of food allergens promotes avoidance behavior
[Leyuan Ma] Vaccine-boosted car t crosstalk with host immunity to reject tumors with antigen...
มุมมอง 49211 หลายเดือนก่อน
[Leyuan Ma] Vaccine-boosted car t crosstalk with host immunity to reject tumors with antigen...
[Olga Zimmermannova] Restoring tumor immunogenicity with dendritic cell reprogramming
มุมมอง 315ปีที่แล้ว
[Olga Zimmermannova] Restoring tumor immunogenicity with dendritic cell reprogramming
[Zeribe Nwosu] Uridine-derived ribose fuels glucose-restricted pancreatic cancer
มุมมอง 296ปีที่แล้ว
[Zeribe Nwosu] Uridine-derived ribose fuels glucose-restricted pancreatic cancer
[Jesus Corria-Osorio] Orthogonal cytokine engineering enables novel synthetic effector states...
มุมมอง 165ปีที่แล้ว
[Jesus Corria-Osorio] Orthogonal cytokine engineering enables novel synthetic effector states...
[Khalid El Bairi] A Focus on Plagiarism and Predatory Publishing
มุมมอง 108ปีที่แล้ว
[Khalid El Bairi] A Focus on Plagiarism and Predatory Publishing
[Maria Cecilia Canesso] Dendritic cell-T cell interactions driving immune responses to food
มุมมอง 261ปีที่แล้ว
[Maria Cecilia Canesso] Dendritic cell-T cell interactions driving immune responses to food
[Jorge Galeano ] 𝗘𝗳𝗲𝗰𝘁𝗼 𝗱𝗲 𝗹𝗮 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝘁𝗮 𝗶𝗻𝘁𝗿𝗮𝘁𝘂𝗺𝗼𝗿𝗮𝗹 𝘀𝗼𝗯𝗿𝗲 𝗹𝗮 𝗵𝗲𝘁𝗲𝗿𝗼𝗴𝗲𝗻𝗲𝗶𝗱𝗮𝗱 𝗲𝘀𝗽𝗮𝗰𝗶𝗮𝗹 d𝗲𝗹 𝗰á𝗻𝗰𝗲𝗿
มุมมอง 99ปีที่แล้ว
[Jorge Galeano ] 𝗘𝗳𝗲𝗰𝘁𝗼 𝗱𝗲 𝗹𝗮 𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗼𝘁𝗮 𝗶𝗻𝘁𝗿𝗮𝘁𝘂𝗺𝗼𝗿𝗮𝗹 𝘀𝗼𝗯𝗿𝗲 𝗹𝗮 𝗵𝗲𝘁𝗲𝗿𝗼𝗴𝗲𝗻𝗲𝗶𝗱𝗮𝗱 𝗲𝘀𝗽𝗮𝗰𝗶𝗮𝗹 d𝗲𝗹 𝗰á𝗻𝗰𝗲𝗿
[Zoé Christenson Wick] Manipulating single-unit theta phase-locking with PhaSER: An open-source tool
มุมมอง 130ปีที่แล้ว
[Zoé Christenson Wick] Manipulating single-unit theta phase-locking with PhaSER: An open-source tool
[Niamh B. McNamara] Microglia regulate central nervous system myelin growth and integrity
มุมมอง 522ปีที่แล้ว
[Niamh B. McNamara] Microglia regulate central nervous system myelin growth and integrity
[Sebastiaan de Schepper] Perivascular cells, microglial phagocytosis, synaptic engulfment via SPP1
มุมมอง 466ปีที่แล้ว
[Sebastiaan de Schepper] Perivascular cells, microglial phagocytosis, synaptic engulfment via SPP1
Explains autonomous PB&J's. Next question for a TD.
Sehr wichtiges Thema wurde bisher nicht ernst genommen....
Thank you for a great talk!
Topic is underrated which itself is an understatement!
such a wonderful work👌👌👌
Apolipoprotein E4 is associated with improved cognitive function in Amazonian forager-horticulturalists with a high parasite burden www.ncbi.nlm.nih.gov/pmc/articles/PMC5349792/ We know parasites stimulate T regulatory cells expression.
Great !!
I have RNAseq data from a mixed backgroud...how can we collaborate on this? I am new into this type of research and I would like to work with you on this data
Beautiful work
Dissection de la souris Dissection de la souris(thymus , la rate)th-cam.com/video/mUns1NEaB-4/w-d-xo.htmlsi=YlBQGUyabhsRIknE
someone know which are the paper that they talk about
yes this is the link to the paper: www.nature.com/articles/s41596-020-0353-1
How did they get expression to stay limited to the SEC layer despite using a ubi promoter??
8:00
Promo`SM ☹️
One of my favorite papers, great work! 🧬📠
Thank you! Cheers!
Bravissima
Great talk!
Just wondering, are Pexidartinib levels controlled for in these studies? Could the drug itself in combination with epileptogenic factors provoke seizures?
😍😍😍😍😍😍
great platform, how can I know the latest meeting? do you have a group or where do you share your meeting numbers. I really appreciate it and thanks for your efforts.I am looking forward to your notice
thanks please see our website openboxscience.org
great platform, how can I know the latest meeting? do you have a group or where do you share your meeting numbers. I really appreciate it and thanks for your efforts.I am looking forward to your notice
Hi you can follow our social networks in twitter facebook or if you want to fill the next link you will automatically receive the info of the talksdocs.google.com/forms/d/e/1FAIpQLSdjjZy-fS8j0Lq7nTy-JjOJb2Yq18oTqH1SfSIklujpG_ahkQ/viewform
good morning, I hope you can answer me. I performed a lymphocyte test and found that I had a deficiency of cd25 il2. what can it cause? thanks for your kind response.
Is the Gwas data and genotype data independent of each other? In the part of Calculating the polygenic risk score.
Hi, you may have to contact the authors directly, thanks!
Do this mutation work the same as for mouse CSF1R?
Hi, you can contact her via twitter @Sonia_Lombroso
Dear Daniel, I am currently integrating scRNA-seq from multiple public datasets (Peng, Steele et al etc). I was trying to find your datasets (matrix/barcodes/genes) but was unsuccessful. Is there a repository to access these data? Thank you.
Hi, you might contact him in LinkedIn www.linkedin.com/in/daniel-cui-zhou-713621204
Make sure to subscribe to this dude!! Need views? -> 'promo sm'.
Thank you for such amazing video; it's nice to be able to count on you.
Very informative!
I just found out about this and how did I not know this before. Like, holy. Wow. Incredible. Just. Wow.
Great presentation! Thank you for uploading :)
25:24 "Active ribosomes are not found in the lumenal spaces" > Are you sure?? go check your mitochondrial lumen (aka mitochondrial matrix). Cheers
Great work look forward to reading more of your work.
I came to this from Kevin Folta. Thanks so much for making this. It’s fascinating.
Amazing discovery! I have a feeling it will revolutionize biology as we know it.
Also great channel! keep the great talks coming!
Yes, I have the same feelings Maram
💦 𝓟Ř𝔬𝓂𝔬𝐒ϻ
ᴘʀᴏᴍᴏsᴍ
Ryan is Ryan!!!!! ❤❤❤
Ryan, the best! ❤
great video, if you want yo grow your channel reply here,
Awesome Dr Choi, it seems like i have been reading your NAture protocol paper title "A guide to performing Polygenic Risk Score analyses".
Yes!! Lassosum2 is also fantastic~
Thanks to both speaker and Open Box Science. Very interesting.
Very awesome work and discovery!!! Chemistry, in this case a very simple one, can really transform how we can derive information from simple experiments like the one ran on the gel. I can think of a hundred more experiments on how that clicked Azido-sugar can be used to further this field. Especially test them ex vitro and in artificial non-living systems, to see whether the biochemistry can still work.
Keep up good work and thanks for presentation 😊
you speak waaay too fast. amazing work, this really is a breakthrough to a brighter future.
👏
Nice 😎
nice work
Neha 11:00
Nice work by the team
microglia does not eat OPC.