วีดีโอ

Symplyctosomomorphism is 3, coordinate ,non symmetric anteforbackward eye prismatic ix,iy,ix,(smaller)iy(longer),iz, f(x)=x to power -2z, interpolTion of an additional false pair of constriction in i curve.

2738 Sid Mills

The fox glove plant is known to strengthen the heart could this be analysed to see its effect on myosin?

Why was omecamtiv mecarbil not approved?

thank you so much for sharing

Beautiful talk

I am Swapnil Pradhan, Assistant Professor, Department of Microbiology, Ramnarain Ruia Autonomous College. Our College faculty and Students have been attending TNQ lectures since 2020. It is a great place for us to listen to the Nobel laureates, listening first hand information about their research, their journey. These talks are very inspiring for students and young teachers. Logistics are also very well taken care by the organisers everytime. Thank you very much and congratulations to the entire team.

We too , AIIMS fraternity look forward to hearing you Distinguished Sir We also are grateful for the excellent presentation by Dr Holly Ingraham yesterday, enthusing and inspiring our students and scholars to to do good science good medicine and do good….

Why is it not happening in Delhi? Any scope of attending it online?

I think Google trust in science for all. If that is so, please arrange a webcast of any of the two lectures. It is just not possible, both financially and time wise, to travel intercity and attend those lectures. Specially for private university teachers like me. Best regards Prabuddha Gupta Kolkata, India

Life Science research with AI is inspiring! Looking forward to the lecture!

the hardy-weinnberg's equillibrium is mismatched Quantitaviley in the population of an ant having translational mis-sense mutation when a pair of false walking will legs appear on the left side with a quite different leg structure which is commonly normally observed on the during locomotion of the ant. Hardy-Weinberg's equillibrium ignores the mis-sense of mutation, in Population genetics equillibrium in which the ribosomes' structure with its ribosomal RNA and protein are interacting with the Transfer RNA generating mismatching anti-codons to express proteins which represent the wrong analogy of the ant's normal alternating tripod gait becoming its own ill-opposite, and non-tandemly translational if both protein synthesis of shorter than the longer of the false pair of walking legs whose photo image is non-superimposable makes one wonder whether the ribosome of the mis-sense mutant is alive or dead at the same time..In other words it is having both dead or alive ribosomes which appear when the DNA guanine is changed by another purine with the differe structure of a purine called the adenine. Therefore the functional role of the early ribosome does both the false function of making false proteins and prematurely terminating functional properties of the shorter walking growing chain of protein by the mis-sense ribosome-ribozyme complex as well. I Think that atomic resolution combined with x-ray crystallography of both the pair of false walking leg's protein that is expressed by the information transcribed from DNA to the information in the messenger RNA and finally translating the genetic code onto ribosomes modifying the shape of protein misfolding into a,pair of chirally false walking legs on the left half the mutant. Therefore,there is no symmetrical pattern counterpoint on the right half of the x-ray crystallographic crystals in the 80S ribosomes of the mis-sense mutation. This hasn't fundamentally brought the Hardy-Weinberg's linkage equillibrium of relating any moleculer ruler to the mis-sense genotype and phenotype correspondingly in this relationship respectively.

Looking forward!

When I first saw an ant moving on a pair of false walking legs merged to the left first thoracic leg and the left antenna ,I realised that,that was a mis-sense mutation ,because the left side of the ant's body now is not symmetrical to its right side. So this observation made me realize that the ant's DNA had a mis-sense mutation,in which a guanine nucleotide base is chsnged to another purine nucleotide-an adenine.This was transcribed into the messenger RNA, which now begins to read the incorrect codon CCG, instead of the correct mRNA codon UCG,as a result the ribosome translates the incortect vodon which contsined an imvorrect amino acid-proline instead of the correct serine amino acid. We moved from The information of the gene to the information of the pair of false walking leg protein chains as a result of mis-sense mutation. Afterwards I checked at the Genetic codon table and found , I was correct.The symmetry of an ant moving on alternating tripod locomotion is changed in the mis-sense mutation which moved both ante-forebackwardly with both the shorter and longer leg of the three dimendionsal structural shaped of the 2 fifferent sized proteins improperly folded by the ribosome's translatiosnal machinary that fails to to discriminate between non-isomorphous in the 2 different rates of rRNA-tRNA interaction in this case of mis-sense mitation .The clover leaf tRNA anticodon stem loop shape which carries an incorrect amino acid proline, instead of serine is not symmetrical and its mirror-image is non-superimposable,somewh -at similiar to the analogy of 2 ribosomal subunits in this mis-sense ant mutation in a bacterial 30S subunit and 50 S misshapen configuration in the x-ray crystallographic studies of Dr.Venkatraman Ramakrishnan' 3-D atomic structure of the 70S ribosome in Thermus thermophilus. I thank you and tnq for delivering in my you tube the designated lectures by the renowned nobel lauteate for taking us thru an exhilarating journey into the atomic structure of the 70S Ribosome in the bacterium Thermus thermophilus and also shared the prize with Ada Yonath(a woman) and Tom Steitz. Unlike other systems where the possibility of self-correction, instead, it is not bad to be wrong, but it is definitely unforgivable to deliberately falsify the truth in the case of the person who for the first time takes the photo image of an ant moving on a pair of false-0walking legs after the front left first thoracic leg merges with the left antenna that produces the mismatch between the messenger RNA codon with the anticodon in the transfer RNA(tRNA).This results in a non-superimposable mirror image of the missense photo image of the ant. In a sense this is the only example that throws light on the ribosome in action when it has a mis-sense mutation. My question is very simple:"Why cant we see the ribosome structure in such mis-sense mutation which binds a pair of false-walking legs to both the left antenna and the 1st left foreleg making alternate locomotion by tripod gait. Firstly,the right first foreleg starts the first step relatively to the corresponding left last hindleg forming 2 groups of Three alternating steps with both of the sides of the ants middle leg.It will be interesting and educative to help make a video of the mis-sense mutant in ante-forebackward Locomotion on misshapen protein folding of the normal 3 pairs of legs.How does the x-ray crystallography help in figuring out the folding of the false pair of walking legs' amino acid sequence shapes with the help of a specific stop codon to prematurely stalling the ribosome to make the shorter false walking leg in the pair. Is the ribosomal RNA shape into a double stranded Structure folded upon itself if an ant having the mis-sense mutation was considered to show the atomic structure of both subunits ,of 5he 80S ribosomesi.e.6oS(large subunit) and 4oS subunits( small ribosomal subunit) in the eukaryote , for,e.g., the mismatch seen between the two codon and anticodon bases, as a working model for atomic structures of eukaryotic Ribosome .Thank you.I remain, My e-mail.address is : ml.arunkumar.metipallearunkumar@gmail.com

Wonderful talk! Thanks for sharing

Like caloric, humors, phlogiston and luminiferous ether the radiative greenhouse effect theory is bogus as is the CO2 driven climate change and global warming fear mongering stacked on top of it.

Very informative.. Thank you

I was actually thinking to record in the TIFR hall, Mumbai..I'm glad I didn't have to take the pain to regret Sirs sense of humor is unwavered like how he narrated his transition phases ..my first audio book ever and the difference the author himself was narrating the story..kudos! Tnq looking forward to more lectures

Thanks for uploading. A very engaging lecture. I have been following Dr Venki Ramakrishnan since he was awarded nobel prize.

Made my day

Please post all full length lectures... I'm eager to watch all. #thankyou TNQ

Thank you

I would like to see the IISc, Bangalore lecture. Can u upload the same please?

Thanks for uploading. I was in the TNQ distinguished lecture series held at AIIMS, NEW DELHI in 2020. Will you please upload his lecture at Aiims new Delhi?

Can someone post full lecture link?

Please turn the live seminar public. We'd like to show this amazing seminar to the students who missed out on it.

Hi, I could not attend yesterday's talk. Could you please upload the video of the lecture? It would be really helpful. Thanks!