Resident Evil 7: Biohazard follows Ethan Winters, a civilian searching for his missing wife, Mia. Ethan receives a cryptic message from Mia, leading him to a derelict plantation mansion in rural Louisiana.
Upon arrival, Ethan discovers the mansion is inhabited by the Baker family, who have been infected with a mysterious virus. As Ethan delves deeper into the mansion, he encounters horrific creatures and uncovers a sinister plot involving Umbrella Corporation and a new, terrifying threat.