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A Beginner's Guide to Bioinformatics_SG
เข้าร่วมเมื่อ 11 ก.ย. 2021
Identifying Physical and Chemical properties of a protein from its sequence
This video provides an overview regarding how to use the ProtParam tool; which allows the computation of various physical and chemical parameters for a given protein sequence. The computed parameters include the molecular weight, theoretical pI, amino acid composition, atomic composition, extinction coefficient, estimated half-life, instability index, aliphatic index and grand average of hydropathicity (GRAVY).
มุมมอง: 253
วีดีโอ
Identification of Conserved Domains
มุมมอง 7K3 ปีที่แล้ว
This video guides the viewer through the steps of identification of conserved domains which are of functional and evolutionary significance using an amino acid sequence.
Exploring Evolutionary Relationships amongst Orthologues
มุมมอง 2523 ปีที่แล้ว
This video provides you with a glimpse of identifying orthologous sequences for a query sequence and how to formulate a phylogenetic tree using the identified sequences using two servers - EGGNOG and CLUSTAL Omega
Signal Peptide Prediction
มุมมอง 2.7K3 ปีที่แล้ว
This video provides an overview of the Signal P server and how to use it for sequence based prediction of the presence/absence of signal peptides.
Cello Submission and Analysis
มุมมอง 3373 ปีที่แล้ว
This video provides an overview of the Cello Server and how to analyse sequence based data using it.
Analyses of MicroRNA sequences
มุมมอง 1983 ปีที่แล้ว
This video provides a simple overview as to how you can generate the secondary structure of an RNA sequence (here Precursor miRNA sequences have been used for demonstration) and identify Repetitive elements in those sequences
Inducing Mutations in Protein Structures
มุมมอง 1.9K3 ปีที่แล้ว
This video provides an insight into a simple protocol for inducing changes / mutations in protein structures using the SWISS - PDB viewer or DEEP VIEW tool.
Eggnog Mapping & Clustal Omega
มุมมอง 7533 ปีที่แล้ว
Finding Orthologs for a Sequence and evaluating their Evolutionary Information
Obtaining Interacting Partners using STRINGDB
มุมมอง 2413 ปีที่แล้ว
This video explains how to use the String database for generating information regarding the possible interacting partners for a particular protein of choice
Exploring NCBI
มุมมอง 2593 ปีที่แล้ว
This video takes you through a tour of NCBI and its essential integrated databases. A must watch for the beginners in Bioinformatics
Sir if we upload 5000 protein sequence in this software how we can download all the sequences together having signal peptide
Neha, You need to submit the FASTA format of the sequences in a contiguous manner one after the other and the predictions will be made in a sequence-specific manner.
Is the conserverd domain active site of enzyme?
Not necessarily
Really helpful thank you
if i need to download data from eggnog what file should i use? could you explain a litte about it? thank you very much
Irene, you can download the annotation files in the form of an EXCEL sheet from the result page
Thanks for this video, good work, please upload more video like this on bioinformatics....🙏🏼😊
thanks for your explication, I have a question Please, after sequencing my DNA, I obtain my DNA sequence, so when i search the Amino acid sequence, i found it without chain, for example, for the first Amino acid to amino acid number 3000. how can i devise my sequence into chains, if you know some website please.
You have to perform homology /comparative modelling to execute your query. Please try SWISSMODEL
This was very helpful thank you!
Thanks Taryn