วีดีโอ

Sound craps out at 14:19 :((

Predating Vaccination, there was smallpox inoculation(variolation). Cotton Mather had an African enslaved man Onesimus who knew of the treatment in Africa.

Thank you for always helping students from all over the world. Do you have any textbook or any place where I can get exam like practice exercises? I'm really making it because of your throughly explained lectures!

Thanks that clears a lot up!

Since so many different TCRs are made initially, many will bind to proteins (or other antigens) on the cell surface that are not MHC. How are only those cells selected with TCRs that bind to MHC and not also those that bind to some other protein (say EGFR) on the cell surface?

Is there evidence for antigen presentation by human neutrophils?

You say that we have 10^16 B different possible B cells and that we have one of each circulating in our bodies. But in a previous lesson you showed a table that said we have only 10^10 B cells in total in our body, which is a million times less.

Your mike was dead, the video clips have sound. Guess I will re-watch last year lecture.

1:36 lecture proper

Great... very helpful as always.

U r amazing! Thank you for making this subject understandable

❤

Thanks for your videos 📹 I really love your course please continue ❤️

Dear Dr. Barker, your series on basic immunology and beyond is a wonderful contribution to our understanding of this vast, fascinating, and elaborate field. Words cannot thank you enough for your generosity in propagating your knowledge to your students and other workers in the field.

is this an undergrad or graduate-level course?

Sorry, im not one of yours. Biochemistry from Ireland. Loved the slides How does the expression of chemokine receptors like CCR7 and CXCR3 influence the selective homing of naïve versus effector T-cells to secondary lymphoid tissues and sites of inflammation? Sorry if that sounds wrong, I'm trying to learn.

No audio

The audio seems to be missing!

Can you have localized Th2 activation in the GI tract without any other locations involved? EG, mast cell activation in the gut only?

Thank you for another wonderful lecture Dr. Brianne.

Excellent

You my friend are going to get me through my immunology class. Lots of people do great detailed overviews of the big picture, but you're the best lecturer I've found who gets into the granular, nitty gritty molecular scale stuff.

nice

Great lectures keep posting!

I'm a postdoc and I find this very helpful. I'm getting back to basics now.

Thank you so much, Dr. Barker !

Your lectures are precious.

Such nice lectures and so very few persons watching then. I'm glad I'm watching.

Thank you, Dr. Brianne. Your lectures are very elaborate and simplified. I hope to see you face to face one day.

It Really helped with the presentation 😅 thank you

Thank you sooooo much❤

Thank you Dr. Barker! Very nice lecture!

This has been favorite ever ❤❤❤🎉🎉

SARS2 down regulates MHC1 do you think this could be driving some long covid possibly being chronic infection?

Hey, Grade 12 student here, I've been interested in immunology for a long time now. Are there any books or texts you would recommend? 💗

very educational

As every year, outstanding lectures, thank you!

Brianne, you say here that the only function you care of IgD is that informs about if it just came out from the bone marrow or not. Is not IgD overexpressed when the B cell goes anergic in the periphery due to a lack of the second stimulus? I follow your lectures and the podcast Immune, so I do not know where I get this idea from. Anyway, thanks for making your lectures available to everyone in the world.

I understand how random events can cause the B cells to produce huge variety, but what is the process whereby the antibodies have two identical branches? Also how can dimers and pentamers be produced, with some classes of antibody?

Professor Baker, it seems that Lesson 12 is missing. Would it be possible to upload that lesson? Thank you very much. I enjoy your lectures-they are clear and interesting.

I wish I had of startled this series 3 years ago.

Omg! Thanks 🙏🏼 you

🥰Thank you!

If you have allergic response localized to gut, would that be igA mediated?

Thank you for making these lectures available on TH-cam. I enjoyed watching and learning from them.

Thank you. Great series of lectures. Appreciated.

Thank you so much, Dr . Barker. Super helpful! It would also be great to see what you were writing/drowning on the board

😍

good lecture

Cellular and Molecular Immunology (10th edition)