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I've just created a GitHub repository, you can download the corresponding file from here: github.com/MvonHein/Budget-Impact-Analysis/blob/main/BIM_Tutorial.xlsx

I just made the MIRO board public. You can view it here: miro.com/app/board/uXjVLQFoHZU=/?share_link_id=713729738417

I'm glad you like it :D

My pleasure! :)

Glad it was helpful!

You should be able to download it from this GitHub repository: github.com/MvonHein/Budget-Impact-Analysis/blob/main/BIM_Tutorial.xlsx

That's great to hear :D

That's what I thought when I first looked into this! Luckily that's going to change ;) Thanks a lot for your kind words, this just gave me a big smile :D

Thanks for your comment & all the important questions you raise! Let me try to answer these one by one. - Modelling Software: Yes, Excel is still the the most widely used tool by far to create cost-effectiveness models. Other solutions exist (R, TreeAge, Python), but they're not as popular. - Rare Disease Modelling: We have to make due with what we got! No model is ever perfect, and if the data is "BAD" in the first place, this is never a good place to start your modelling from. However, given the rare nature of some diseases, we simply won't get large datasets of thousands of patients, so we have to use what we got. - VBA: Visual Basic for Applications is Microsoft's programming language that's built into the MS Office Suite of products. For CEMs, we use it to do deterministic and probabilistic sensitivity analysis, and maybe add some user-friendliness features. - Decision Tree Model: Yes, that's on my list! :)

My pleasure :)

Thanks :)

Glad it was helpful!

Thank you, glad you found it useful :)

Thanks for sharing, I appreciate it a lot :)

You're welcome! :)

Thank you, glad you enjoyed it :)

Thanks a lot :D

Agreed, the two concepts are often confused! Disability weights (DW) represent the severity of a health condition. The more severe the condition, the higher the DW. For example, a stroke with no recovery would have a very high DW, whereas a minor hearing loss would have a much lower DW (for reference: in my video I used 0.4 and 0.8 as the DW). The DW is captured in the years lived with disability (YLD) part of the DALY equation, which also considers years of life lost (YLL). DALYs are calculated as YLD + YLL, whereby YLD equals the time an individual experiences the health condition multiplied by the DW. Another good way of thinking about it is like this: QALY: “0” is equivalent to death; “1” represents perfect health. DALY, “0” represents perfect health; “1” equates to death. Hope this helps!

I agree flexible working has become quite standard in recent years, which-in my opinion-was long overdue! For me, a balance between in-office days and WFH works best. I find that I get more stuff done when I’m at home, but seeing people in the office creates personal connections which ultimately contributes to a happier work environment. I’m fully aware, though, that there is no “one-fits-all” type of approach, since we all have different requirements to work around.

That is really motivating to hear, thank you for your kind words! 😊

You can use either Excel or R to create any of these models. Both can generate the results you need, including PSA! Excel is more widely used than R, but learning R is a great skill to acquire as a health economist, so I’d highly encourage you to keep up with that! If you’re keen to dive more deeply into modelling, you could get a copy of this book, which has some practical examples in it: www.amazon.co.uk/Effectiveness-Modelling-Health-Technology-Assessment/dp/3319157434 Alternatively, @TMSnowsill also has some great content on his YT channel that might be relevant for you. I’m also uploading a hands-on modelling tutorial using Excel on the 12th of January, so you might want to stay tuned for that! 😁

I enjoy creating longer-form videos more myself, but I believe there is also value in having condensed formats like the YT short to complement the longer videos. Honestly, I’ve partly started switching to YT shorts to maintain weekly uploads, especially over the holiday season. These YT shorts are quicker to produce and give me more time to focus on videos that will take longer to create. People always have different ways of learning / absorbing new information, so I think having both shorts & long-form videos doesn’t hurt 😊

Thank you, I appreciate it :D

What's your reference for this? I'd be keen to investigate!

I've got no intention of stopping 😉

Thank you for your kind words. The goal is to cover all of these topics in more detail at some point - it might just take me a little while to get there 😄 MA and BIA are high up on the priority list!

Thank you, I appreciate it! Let me know if there's a particular topic you'd like me to explore in more detail!

Happy to hear that you found this introduction to pharma consulting useful, and thanks for commenting! If you can think of other pharma consulting topics would you like to see on this channel, let me know!

Thanks for your comment, I'm very glad this was useful to you. Is there any other topic that you'd like me to cover in one of my next videos?

@@MirkovonHein Yes, I want to learn health economics from basics to advanced level analysis. If you prepare a playlist on that it would more helpful.

@@rakeshanbazhagan3337 Absolutely, playlists are already on my radar! For playlists to make sense I want there to be a bit more content first, so it'll probably be a little while longer until I can logically group similar videos together. But yes, some day in the future I plan on having my videos categorised so that new viewers have a more structured experience :)

Who knows what the future holds... 📖😊

Thank you for your kind words. Reading this just made me smile :)

I'm sure AI soon will be able to give suggestions for how to improve storytelling in presentations as well... I haven't actually used AI much for PPT slides. I'm curious, what AI are you using for your slide decks?

@@MirkovonHein : I meant in the future AI would give content for the ppt as well. I came across a tool by the name Gamma, I haven't used ,but the advert on TH-cam makes me feel it's promising

Thanks for sharing the feedback. You're not the first one to bring this up, so I may make some changes going forward. What's your preference - no background music, different background music, or reduced background music loudness?

Glad you found it useful! Hopefully I provided enough details ;)

@ 😊

QoL can be measured using generic or disease-specific instruments. Common examples of a generic QoL instruments include the EQ-5D and the SF-36. Both are questionnaires that are completed by the patient, which cover various domains. Disease-specific QoL instruments on the other hand are tailored to specific conditions, like the EORTC for cancer for example. On top of these two methods, you could also use direct utility elicitation methods like standard gamble or time trade-off to capture QoL, but using standard surveys, ideally captured within the primary trail of a new drug, is usually easier and therefore preferred.

@@MirkovonHein thanks for detailed response!

Glad you enjoyed it!