วีดีโอ

Alcohol associated hepatitis

Alcohol hepatitis Outflow obstruction

Nocturnal pruritus

Sir, IDAHS with raised ALT can also be an acute hepatitis patient. How to approach then ?

Sir through your Channel , I want to thank Dr . Surender Rana for Saving my life in acute Jaundice of Hepatitis E, -Regards

why patient of ibs-d complains of flue and chest discomfort after defecation

I have been diagnosed with eosinophilic colitis (autoimmune). I can’t find much information about it. Can you do a video about this please 🙏🏽🙏🏽🙏🏽🙏🏽

Amazing presentation !!

Nice video very informative thank you so much

Please try uploading epaathshaala videos if possible. Season 4 is currently ongoing

can we know the name of doctors plz

Amazing channel thank you so much for your contribuition to education :D

If cancer is the king of all maladies pancreatic cancer is the emperor. With imaging modalities and endoscopic techniques early diagnosis seems possible. The development of HPB and Pancreatic surgery, standardisation of resection such as R0,N2 enblock resection, peri-op care and chemotherapy in the peri-operative setting has lead to higher resection rates and better survival.

Excellent talk

Iam suffering from supragastric belching past 2 years.. I can't find any therapist who knows about supragastric belching.. what can I do? Any dr available in kerala ? Iam from kerala

Cristobal Rue

French Belgium criterion lt

I have hpylori I'm following keenly

Good class

Thanku sir

Am I right in saying that much more funds go into the research for pancreatic cancer rather than acute pancreatitis, a grave disease that probably kills as many people as pancreatic cancer does.

ppt slide available .? if yes please upload..

Hi Sir, Could you please suggest me the best DR for this. I have been suffering for past 10 yrs eosinophil gastroenteritis desase. Still not got proper medication. Its repeated every 2-3 months. How i do allergy test.

Excellent explanation. Thank you Vineet sir

👍informative

Excellent overview of an imp yet complex disease. The revised BCLC ( 2020 ) includes upto 5 cm single lesion in A stage and following liver directed therapy stage B disease may be eligible for curative therapy. Whereas BCLC is followed in the west, it’s considered restrictive as regards surgery / curative therapy in Asia. Several Asian centers have given their own staging & management algorithms ie Korea, Japan, China, Hong Kong. In the developing countries with limited facilities for transplant liver resection of operable intermediate stage hcc would be highly desirable. Finally an HPB surgeon to highlight the role of Surg, the only curative option would have been appropriate.

Wonderful presentation.

Aud ,heavy drink and Binge drink

Cage and audit c

Dsm4 alcohol abuse and dependence Dsm 5 a use d/o

Amt calculator

Aud Detection

Sir plz keep taking regular lectures as none of the institutions are teaching. We will be highly obliged.

Thank you sir. We need teachers like you

You are a treasure of information & inspiration Pankaj sir

Dr Abby Philips 👍

Thankyou doctor

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🎯 Key Takeaways for quick navigation: 00:11 🎙️ *The 11th ISC Masterclass focuses on managing hepatocellular carcinoma (HCC).* 01:16 🗣️ *Dr. Anil Arora, a renowned speaker from Sir Ganga Ram Hospital, discusses HCC management, emphasizing prevention.* 08:29 🕵️ *Surveillance for HCC is essential, with criteria including commonality, affordability, acceptability, and effectiveness.* 11:26 🌐 *Ultrasonography is a key surveillance modality, offering high sensitivity in detecting early HCC, especially in countries like Japan.* 13:03 📸 *Radiological diagnosis of HCC, using criteria like arterial phase hyperenhancement, can often eliminate the need for a tissue biopsy.* 15:47 ⚖️ *Biopsy is indicated for indeterminate lesions, and staging considers tumor size, performance status, and liver function.* 19:15 🚑 *Curative therapies for early HCC include ablation, surgery, and liver transplantation, with options like percutaneous ethanol injection and radiofrequency ablation.* 21:10 ❓ *Radiological diagnosis of HCC includes arterial hyperenhancement, total venous washout, and underlying cirrhosis, but not a size less than one centimeter.* 24:57 🩺 *Early diagnosis of HCC involves recognizing well-differentiated carcinoma and assessing fat positivity. PET has no role in early HCC diagnosis.* 25:41 🔄 *Surveillance for HCC in non-cirrhotic patients with portal hypertension depends on thrombosis presence; hypercoagulable state may be a focus.* 26:09 🌐 *BCLC staging system, particularly BCLC, is widely used in India for HCC, validated and considered best. The speaker suggests an easier algorithm as an alternative.* 27:17 🩸 *Larger HCCs, preserving liver function, may not exhibit elevated alpha-fetoprotein. Surgery is the primary curative option, with no significant difference in radiological features based on cirrhosis presence.* 28:13 📉 *AFP of 170 in a <1 cm dysplastic nodule poses a challenge. Replication status check is crucial; if positive, follow-up; if negative, consider further imaging after 2 cm.* 29:30 📊 *Surgical resection for HCC depends on the number, extent of lesions, and Child-Pugh or MELD scores, ensuring low mortality and morbidity.* 31:39 ⚖️ *RFA is comparable to local resection for lesions up to 3 cm. Criteria for major or minor resection depend on portal hypertension and liver function.* 32:18 🔄 *Liver transplantation, particularly meeting Milan's criteria, is a curative option for HCC. Living donor liver transplantation has expanded criteria, including UCSF criteria.* 34:51 🎯 *For multinodular, unresectable HCC with preserved liver function (BCLC B), transarterial chemoembolization (TACE) is a classical local-regional therapy.* 38:23 🎯 *Transarterial radioembolization (TARE) uses microspheres to target hepatocellular carcinoma, showing potential advantages but not universally recommended over TACE.* 39:45 🌐 *Systemic therapy considerations involve sequential use of sorafenib and lenvatinib. Immunotherapy, particularly immune checkpoint inhibitors, shows promise.* 43:44 🤝 *Prevention of HCC includes lifestyle modifications, hepatitis B vaccination, and treating hepatitis B and C. Coffee consumption may reduce HCC risk.* 44:52 🧬 *Liquid biopsy, detecting tumor-associated protein biomarkers and genomic patterns in extracellular vesicles, shows promise for early HCC diagnosis.* 51:43 🩹 *Use of TCP and Alpha-fetoprotein fraction L3 in management helps characterize lesions likely to recur, guiding decisions on liver transplantation.* 52:25 🧐 *CT, MRI, and EUS are crucial for distinguishing multicentric HCC from a single HCC with multiple intrapatic metastases. Prior imaging history is essential for accurate diagnosis.* 53:54 🚫 *Non-cirrhotic HCC requires biopsy for diagnosis, as radiological criteria are specified only for cirrhosis cases. Three requisites include underlying cirrhosis, lesion >1cm, and arterial enhancement with venous washout.* 54:50 🩸 *Fibroscan's role in HCC diagnosis is minimal, and its advantage diminishes after obtaining CT and MRI results. Diagnosis is effectively done through CEUS, CT scan, and MRI.* 55:31 📊 *Comparison of Hong Kong (HKLC) and Barcelona Clinic (BCLC) liver cancer scores in Indian patients varies across centers. Validation is needed, and deviations require prospective evaluation.* 57:24 🔄 *Post-SVR HCV cirrhosis surveillance frequency should remain consistent. Starting direct-acting antivirals (DAAs) at HCC diagnosis aids recovery, reducing subsequent HCC development.* 59:06 💡 *Surveillance strategy for alcoholic cirrhosis and NASH cirrhosis aligns with incidence and cost-effectiveness. Non-cirrhotic NASH surveillance is subjective, considering individual factors.* 01:00:17 🔄 *HCC management algorithm: Begin by assessing performance status (PS), presence of extrahepatic spread, and lesion size in Milan criteria. Tailor treatment based on PS, tumor size, and underlying cirrhosis.* 01:06:28 ☕ *Coffee reduces oxidative stress, potentially lowering HCC risk. Its impact is associated with stimulating MAPK3 kinase and decreasing inflammation caused by etiological agents.* 01:08:10 🚫 *Sorafenib's efficacy in HCC treatment is not significantly enhanced by adding statins. Clear risk reduction data is lacking for statins in HCC prevention.* 01:08:59 📊 *Des-γ-carboxy prothrombin (DCP) and Alpha-fetoprotein fraction L3 have limited roles in HCC diagnosis but play a crucial role in prognosis, guiding decisions on surgery, recurrence, and transplantation.* 01:09:12 🩸 *In pediatric HCC, management approach is uncertain due to limited experience. Liquid biopsy, recently published, may provide additional diagnostic insights.* Made with HARPA AI