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Learn Biotechnology and Microbiology
Pakistan
เข้าร่วมเมื่อ 26 ม.ค. 2020
Welcome to my TH-cam channel! I am Dr. Ibrar Khan, a Tenured Professor at the Centre of Biotechnology and Microbiology at the prestigious University of Peshawar, Pakistan.
My channel is dedicated to providing high-quality educational content for undergraduate and postgraduate students who are interested in the fields of genetics, cellular signaling, proteomics, microbial diseases, microbiology, medical biotechnology, and immunology. As a highly knowledgeable and experienced expert in these subjects, I am passionate about sharing my expertise and insights with my audience to help them gain a better understanding of these complex topics. My videos cover a range of subjects and are designed to be both informative and engaging. As a student, you can deepen your knowledge in these fields and my channel is the perfect place for you to learn and explore. I am committed to helping my viewers achieve their academic and career goals.
Thank you for joining me on this journey
My channel is dedicated to providing high-quality educational content for undergraduate and postgraduate students who are interested in the fields of genetics, cellular signaling, proteomics, microbial diseases, microbiology, medical biotechnology, and immunology. As a highly knowledgeable and experienced expert in these subjects, I am passionate about sharing my expertise and insights with my audience to help them gain a better understanding of these complex topics. My videos cover a range of subjects and are designed to be both informative and engaging. As a student, you can deepen your knowledge in these fields and my channel is the perfect place for you to learn and explore. I am committed to helping my viewers achieve their academic and career goals.
Thank you for joining me on this journey
L55. The Differences Between B-cell Receptor (BCR) and Secreted Antibody
#BCellReceptor #Antibodies #Immunology #AdaptiveImmunity #BCells #Biology #ScienceEducation #MedicalScience #Immunity #cellbiology
B-cell receptors (BCRs) and secreted antibodies are both crucial components of the adaptive immune response, but they serve different roles and have distinct characteristics.
BCRs are membrane-bound immunoglobulins found on the surface of B cells, functioning as the primary receptor for antigens. They are involved in the initial recognition and binding of specific pathogens, which triggers B cell activation and proliferation. Upon activation, B cells undergo a process called class switching, leading to the production of secreted antibodies, which are released into the bloodstream.
Unlike BCRs, secreted antibodies are soluble proteins that can circulate freely and bind to antigens in the extracellular environment. This binding can neutralize pathogens, mark them for destruction, or prevent their entry into cells. Additionally, while BCRs are specific to the B cell they originate from, the diversity of antibodies produced allows for a broad response to various pathogens. Thus, BCRs are essential for antigen recognition and B cell activation, while secreted antibodies play a vital role in the effector phase of the immune response.
B-cell receptors (BCRs) and secreted antibodies are both crucial components of the adaptive immune response, but they serve different roles and have distinct characteristics.
BCRs are membrane-bound immunoglobulins found on the surface of B cells, functioning as the primary receptor for antigens. They are involved in the initial recognition and binding of specific pathogens, which triggers B cell activation and proliferation. Upon activation, B cells undergo a process called class switching, leading to the production of secreted antibodies, which are released into the bloodstream.
Unlike BCRs, secreted antibodies are soluble proteins that can circulate freely and bind to antigens in the extracellular environment. This binding can neutralize pathogens, mark them for destruction, or prevent their entry into cells. Additionally, while BCRs are specific to the B cell they originate from, the diversity of antibodies produced allows for a broad response to various pathogens. Thus, BCRs are essential for antigen recognition and B cell activation, while secreted antibodies play a vital role in the effector phase of the immune response.
มุมมอง: 14
วีดีโอ
L54: The Structure of Antibody/Understanding the Structure of Antibodies: The Body's Defenders
มุมมอง 24วันที่ผ่านมา
#Bcells #immunology #immunesystem #antibodies #antibodystructure #immunoglobulins #healthcare #pathogens #biotechnology #microbiology #structureofantibody Antibodies, also known as immunoglobulins, are specialized proteins produced by the immune system to identify and neutralize foreign objects like bacteria and viruses. Here’s a detailed look at their structure: 1. Basic Structure: Shape: Anti...
L53: The developmental stages of B-cells/Adaptive Immune System (Part 2)
มุมมอง 2014 วันที่ผ่านมา
#B-cells #Bcells #immunology #adaptiveimmunity #BCellDevelopment #immuneresponse #PlasmaCells #memoryBcells #bonemarrow #lymphocytes #immunehealth #biology B cells, a crucial component of the adaptive immune system, undergo a series of maturation stages as they develop from progenitor cells in the bone marrow to fully functional immune cells. Here’s a comprehensive overview of these stages: 1. ...
L52: The developmental stages of B-cells/Adaptive Immune System (Part 1)
มุมมอง 3421 วันที่ผ่านมา
#B-cells #Bcells #immunology #adaptiveimmunity #BCellDevelopment #immuneresponse #PlasmaCells #memoryBcells #bonemarrow #lymphocytes #immunehealth #biology B cells, a crucial component of the adaptive immune system, undergo a series of maturation stages as they develop from progenitor cells in the bone marrow to fully functional immune cells. Here’s a comprehensive overview of these stages: 1. ...
What is Guanine Nucleotide Exchange Factor/ What is a GEF and its function
มุมมอง 7928 วันที่ผ่านมา
#GEF #GuanineNucleotideExchangeFactors #CellBiology #MolecularBiology #CellSignaling #Biochemistry #GTPase #CellFunction #biology GEFs are proteins that play a crucial role in cell signaling. They facilitate the exchange of GDP for GTP on small GTPases, which are molecular switches that regulate various cellular processes. When a GEF binds to a GTPase, it promotes the release of GDP, allowing G...
L51: The Lectin Complement Pathway/ How the Lectin Complement System works/The MBL pathway
มุมมอง 37หลายเดือนก่อน
#LectinComplementPathway #Immunology #InnateImmunity #ComplementSystem #MannoseBindingLectin #PathogenRecognition #AutoimmuneDiseases #InfectiousDiseases #ImmuneResponse #Biology #MedicalResearch #Healthcare #ScienceEducation #PathwayMechanisms #ImmuneSystemExplained The lectin complement pathway is one of the three primary pathways of the complement system, which plays a crucial role in the im...
L50: The Alternative Complement Pathway/The Complement Pathway
มุมมอง 28หลายเดือนก่อน
#immunesystem #immunology #complementsystem #complementpathway The alternative pathway is the second mechanism by which the complement system can be activated. Like the classical pathway, it culminates in the formation of C5b, leading to the assembly of a membrane attack complex that lyses target cells. However, unlike the classical pathway, the alternative pathway does not require antigen-anti...
L:49: The Classical Complement Pathway of Complement System; Part 2
มุมมอง 33หลายเดือนก่อน
#complementsystem #complementpathways #immunesystem #immunology The complement system is a crucial component of the innate immune system, comprising a network of over 50 proteins found in blood plasma and tissues that work together to identify and eliminate pathogens, damaged cells, and other threats. It operates through three primary pathways: the classical, lectin, and alternative pathways. T...
L48: The Complement System/ Complement Cascade/ Classical Complement Pathway; Part 1
มุมมอง 79หลายเดือนก่อน
#complement #complementsystem #complementcascade #immunology #immune system The complement system is a crucial component of the innate immune system, comprising a network of over 50 proteins found in blood plasma and tissues that work together to identify and eliminate pathogens, damaged cells, and other threats. It operates through three primary pathways: the classical, lectin, and alternative...
L47; Differentiation of monocytes into macrophages and mechanism of action of macrophages
มุมมอง 982 หลายเดือนก่อน
#immunesystem #immunology #innateimmunity #macrophages #monocytes Monocytes, a type of white blood cell produced in the bone marrow, circulate in the bloodstream before migrating into tissues where they differentiate into macrophages. This differentiation is primarily driven by signals from the local tissue environment and involves a series of developmental steps. Upon entering tissues, monocyt...
L46: The origin, development and morphology of macrophages
มุมมอง 342 หลายเดือนก่อน
#immunesystem #immunology #macrophages #biotechnology Origin and Development: Macrophages are vital components of the immune system, originating from hematopoietic stem cells in the bone marrow. These stem cells differentiate into monocytes, which then circulate in the bloodstream. When monocytes migrate to various tissues throughout the body, they mature into macrophages. This transition allow...
L45; Granules of Eosinophils; Eosinophil Cationic Protein and Reactive Oxygen Species
มุมมอง 502 หลายเดือนก่อน
#immunology #eosinophils #biotechnology #antiparasitic #immunesystem Eosinophil Cationic Protein (ECP) is a crucial component of eosinophil granules, playing a significant role in the immune response to parasitic infections and allergic reactions. This protein targets bacteria and single-stranded RNA viruses, demonstrating its effectiveness against a range of pathogens. ECP exists in various gl...
L44; Granules of Eosinophils; Mechanism of action of Major Basic Protein (MBP)
มุมมอง 602 หลายเดือนก่อน
#immunology #eosinophils #biotechnology #antiparasitic #immunesystem Major Basic Protein (MBP) is a key component of the granules found in eosinophils, a type of white blood cell. Its mechanism of action is primarily involved in parasitic infection. Cytotoxic Effects: MBP has cytotoxic properties that can damage and kill a variety of target cells, including parasites and host tissues. It does t...
L3: DNA vs. RNA: What Makes Them Unique
มุมมอง 483 หลายเดือนก่อน
#molecularbiology #biology #dna #rna In 1869, Swiss biochemist Friedrich Miescher made a groundbreaking discovery in the nucleus of white blood cells. He found a substance that was neither protein nor lipid and named it "nuclein." Nucleic acids are termed "acidic" because they can donate hydrogen ions (H⁺) to their surroundings, a trait linked to the phosphate groups in their backbone. Thus, th...
L2: Why the study of differences between Prokaryotic and Eukaryotic Cells is important
มุมมอง 544 หลายเดือนก่อน
#biotechnology #molecularbiology #microbiology #eukaryotic The study of differences between prokaryotic and eukaryotic cells is crucial for several reasons: Understanding Basic Biological Processes: Structure and Function: Knowing the structural differences helps in understanding the specific functions of each type of cell. For example, prokaryotic cells lack a nucleus, which affects how their ...
L1: Differences between Prokaryotic and Eukaryotic Cells
มุมมอง 414 หลายเดือนก่อน
L1: Differences between Prokaryotic and Eukaryotic Cells
L43; Eosinophils: Origins, Morphology, Granules & Acid Phosphatase's Role in Parasite Defense
มุมมอง 475 หลายเดือนก่อน
L43; Eosinophils: Origins, Morphology, Granules & Acid Phosphatase's Role in Parasite Defense
L42: Basophils granules contents/function of Proteoglycans and cell surface receptors(animation)
มุมมอง 365 หลายเดือนก่อน
L42: Basophils granules contents/function of Proteoglycans and cell surface receptors(animation)
L41: Basophils granules contents/function of Heparin; a natural anticoagulant (animation)
มุมมอง 195 หลายเดือนก่อน
L41: Basophils granules contents/function of Heparin; a natural anticoagulant (animation)
L40: Introduction to Basophils; Origin, development, morphology and granules contents (animation)
มุมมอง 605 หลายเดือนก่อน
L40: Introduction to Basophils; Origin, development, morphology and granules contents (animation)
Differences between Apoptosis and Necrosis
มุมมอง 766 หลายเดือนก่อน
Differences between Apoptosis and Necrosis
L39: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 4)
มุมมอง 386 หลายเดือนก่อน
L39: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 4)
L38: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 3)
มุมมอง 516 หลายเดือนก่อน
L38: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 3)
L37: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 2)
มุมมอง 1006 หลายเดือนก่อน
L37: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 2)
L36: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 1)
มุมมอง 826 หลายเดือนก่อน
L36: Extravasation/ Diapedesis; Understanding the Molecular Mechanisms (Part 1)
L35 Neutrophil Extracellular Trap (NETs)/ NETosis (Part 2) Understanding Mechanisms Behind NETs
มุมมอง 1547 หลายเดือนก่อน
L35 Neutrophil Extracellular Trap (NETs)/ NETosis (Part 2) Understanding Mechanisms Behind NETs
L34: Neutrophil Extracellular Trap (NETs)/ NETosis; Understanding the Mechanisms Behind NETs
มุมมอง 3497 หลายเดือนก่อน
L34: Neutrophil Extracellular Trap (NETs)/ NETosis; Understanding the Mechanisms Behind NETs
L33: Tertiary or Gelatinase granules in Neutrophils/ Matrix Metalloproteinases
มุมมอง 657 หลายเดือนก่อน
L33: Tertiary or Gelatinase granules in Neutrophils/ Matrix Metalloproteinases
L32: Mechanism of action of Elastase and Cationic Antimicrobial Proteins/Cathelicidins/ LL-37
มุมมอง 1877 หลายเดือนก่อน
L32: Mechanism of action of Elastase and Cationic Antimicrobial Proteins/Cathelicidins/ LL-37
L31: Mechanism of action of Collagenase and Lysozymes (Secondary Granules in Neutrophils)
มุมมอง 2368 หลายเดือนก่อน
L31: Mechanism of action of Collagenase and Lysozymes (Secondary Granules in Neutrophils)
Well explained
Thank you for your kind words
جزاك الله خيرا ، من مصر
Thank you for your kind words 😊😊
Informative😊
Glad you like it
God bless you
Thank you for your kind words
Thank you!!!
Most welcome
Thank you for the explanation!
You are most welcome
Sir Plz make a video on transcription And replication
I'll make videos on these topics soon
@@learnbiotechnologyandmicrobiol Thanks sir g
@@ShabbirUllah-z3w most welcome
Best explanation ❤
Thank you for your kind words ❤️
Good video 👍
Thank you for your kind words
And please upload more videos on cellular signalling topics
Please watch this playlist. It has a lot of videos on cell signaling pathways and other related topics.th-cam.com/play/PLRb8wAfVVvFK9lDSH17zt6c1llhv-H2va.html
Jazakallah sir❤may Allah give u high rank in jannah
Thank you so much for your kind words
Highly informative lecture, sir! Very lucidly explained, too. Can you please name the textbook/ source from which the content has been derived?
Thank you so much for your kind words. I usually use research and review articles for lectures but I'll share the names of some relevant books soon
@@learnbiotechnologyandmicrobiol Thank you!!
Introduction to Cell Signaling" by David M. Knipe and Peter M. Howley
@@learnbiotechnologyandmicrobiol Thank you again!
Yes sir.❤
Thank you. Keep watching 😄
Good evening! As a Grade 12 student with a strong interest in immunology and biotechnology, I’m currently following Dr. Brianne Barker's Immunology Fall 2024 course on TH-cam. I find your channel particularly valuable as I plan to pursue biotechnology and immunology in my studies, with the possibility of aiming for a PhD. Could you recommend any key books on immunology and biotechnology that would be beneficial at my level? ❤
Good evening. As a Grade 12 student, you may find some concepts challenging at first, but I encourage you to begin your journey with the following essential texts: for immunology, I highly recommend the "Kuby Immunology, 7th edition." For biotechnology, "The Cell: A Molecular Approach" by Bruce Alberts is an excellent foundation.
@@learnbiotechnologyandmicrobiol Thank you so much! I'll check out these books in our school library. I've been interested in immunology for the past five years and have been gradually gathering information and studying during that time to support my long-term goals. Thank you once again <3.
@@ArchyDMiller most welcome. You can contact me any time via ibrarkhan1984@uop.edu.pk
Very informative sir thanks👌
Most welcome
Masha Allah
Thank you
Nice explanation😊
Thank you 🙂. Keep watching
Welcome sir you deserve this gratitude
loved the explanation...seeking for more topics doctor🙌🙏
Thank you for your kind words. Please watch the playlist of immunology on my channel for more topics
Masha Allah big brother i wish i could become a teacher like you! It's me Maria !!!
Thank you for your kind words. You will in Sha Allah
Big brother ❤️
Big brother!!!!! ❤️❤️❤️ I love you its me maria!!!!!!!!!!!!
Thank you ❤️❤️❤️
@@learnbiotechnologyandmicrobiol no problem 😁😃😃😃
Very organized lecture.
Thanks a lot
Very simple english mashallah and outstanding explanation about evidences of the presence of immunity in humans.
Thank you for your kind words. Keep watching dear
Sir ma NY b bs biotechnology Peshawar university se kiya is department se .. ap humry. Senior thy..
Which batch
2010
Sir apky lecture bohat informative hain r bht acha way ha apka
Thank you for your kind words and keep watching 😄😄😄😄
THANK YOU!!! U ARE THE BEST
You're welcome and thank you for your kind words. Keep watching
Excellent presentation 👏👏
Thanks dear
Thank you
You're most welcome
Very good explanation ❤️❤️❤️ from 🇱🇰
Thank you for your kind words. Keep watching
❤
Nice 👍
Thank you dear
I have subscribe to you ❤❤❤
Thank you dear❤️❤️❤️❤️
Really appreciate how you explain complex concepts in a way that's easy to understand. ❤
Thank you for your kind words. I am glad that it was helpful
Great help sir thanku😊 please upload the next video too
Thank you for the nice comment and Most welcome. I'll upload the next video in 3 to 4 days
Beneficial..Thanks
You're welcome!
❤
Please send more vidio like this painfull
I agree that the procedure is painful
😢😅
❤❤❤
Thank you dear
❤❤❤
Thank you dear
Very well explained ❤
Thanks a lot dear 😊
Sir you’re an amazing and most talented gem of our dept and I’m proud of uh fan of your teaching this 4 year of experience in my đẹpt I’ve never ever seen such a punctual person who’s really motivated extraordinarily bestest I’ve no words to explain and I feel if I’ve get a chance or someday when I became rich ill pay you and you’ll teach me the whole science if that became true you’re so intelligent hats off to you 👏❤️kudoos
Thank you so much for your incredibly kind words. It's truly heartwarming to receive such appreciation for my teaching efforts. I'm delighted to hear that you find my dedication and motivation inspiring, and I'm honored to have made a positive impact on your learning journey. Your commitment to learning and your generosity of spirit shine through in your comment. It's students like you who make teaching such a rewarding profession. While the idea of teaching you the whole science sounds like an exciting prospect, remember that the greatest reward for any teacher is seeing their students succeed and thrive in their endeavors. Your determination and eagerness to learn are what truly matter. I look forward to continuing this journey of knowledge and discovery together. Thank you once again for your kind words and encouragement.
Is there any faster way of doing this? Im studying for a competitive exam and we have 1 minute per question. So how can i save time doing this?
This is the quickest way to do it dear, practice it a lot and you will be able to solve your exam question in a minute
@@learnbiotechnologyandmicrobiol Okay 👍. Thank you very much for this video. It’s very helpful I understood what to do.
@@ShivenStudy Most welcome. If there are any further questions or queries, you can contact me anytime
Mashallah..
Thanks dear
Mashallah... You are doing great
Thank you so much 😊
Es posible entender la diferencia entre los microarreglos de proteinas
Yes there are some differences between protein and DNA microarrays and I will soon make a video on DNA microarray. The basic difference is DNA microarray is an arrangement of DNA spots (in picomole) attached to a solid surface for the detection of DNA (gene) while in a protein microarray, collection of purified proteins, antibodies, affibodies etc are attached on a solid surface.
Mashallah ,simply explained.Thankyou Sir
You are most welcome dear
Nice video sir
Thank you dear
Masha Allah
Thank you dear
Good
Thank you