Axial
Axial
  • 1 001
  • 329 187
Scientist Stories: Fabian Theis, Machine Learning and Systems Biology
Fabian Theis conducts research in the field of computational biology. The main focus of his work is the application of machine learning methods to biological questions, in particular as a means of modeling cell heterogeneities on the basis of single cell analyses and also of integrating “omics” data into systems medicine approaches.
Professor Theis received PhD degrees in physics and computer science in 2002 and 2003 respectively. After working as a postdoc in Regensburg, Tokyo and Tallahassee, he took up a position as Bernstein Fellow at the Max Planck Institute for Dynamics and Self-Organization in Göttingen. He then joined the German Research Center for Environmental Health, Helmholtz Zentrum München, where he was a group leader at the Institute for Bioinformatics and Systems Biology for six years. In 2009 he was became an Associate Professor at the Chair of Applied Mathematics, TUM. Since 2013 he has been a Full Professor of biomathematics at TUM, where he holds the Chair of Mathematical Modeling of Biological Systems, and director of the Institute of Computational Biology at the Helmholtz Zentrum München.
scholar.google.com/citations?user=sqWpn2AAAAAJ&hl=en
#biotechnology #science #vc #startup #startups #startupideas #biology #biotech #chemistry #business #speech #speeches #investing #investment #lifescience #casestudy #scientist #scientists #inventors #inventor #inventions #invention #research #innovation #siliconvalley #entrepreneur #entrepreneurship #entrepreneurs #healthcare #genomics #genetics #history #biologia #technology #tech #founderstories #founder #founders #founderstory #scienceandtechnology #sciencestory #stories #bioengineering #engineering #engineer #biochemistry #discovery #discover #technical #health #education #educational #learning #learn #podcast #podcasts #podcasting #podcaster #technews
Axial Newsletter: axial.substack.com/
Build with Axial: build.axialvc.com/
linktr.ee/axialxyz
มุมมอง: 233

วีดีโอ

Scientist Stories: Thomas Lanyon-Hogg, Chemical Biology in Drug Discovery
มุมมอง 673 หลายเดือนก่อน
Thomas Lanyon-Hogg is the Principal Investigator at the Department of Pharmacology, University of Oxford. scholar.google.com/citations?user=eHXKEIwAAAAJ #biotechnology #science #vc #startup #startups #startupideas #biology #biotech #chemistry #business #speech #speeches #investing #investment #lifescience #casestudy #scientist #scientists #inventors #inventor #inventions #invention #research #i...
Founder Stories: Bobby Gaspar, Manufacturing Hematopoietic Stem Cells
มุมมอง 843 หลายเดือนก่อน
Bobby Gaspar is a world-renowned scientist and physician and accomplished strategic and organizational leader with more than 25 years of experience in medicine and biotechnology. He is co-founder and chief executive officer of Orchard Therapeutics, a global gene therapy leader recently acquired by Kyowa Kirin with the goal of accelerating the delivery of new gene therapies to patients around th...
Scientist Stories: Dana Pe'er, Single-Cell Gene Regulation
มุมมอง 1723 หลายเดือนก่อน
Dana Pe'er is currently the Chair and Professor in Computational and Systems Biology Program at Sloan Kettering Institute, and regarded as one of the leading researchers in computational systems biology. Previously, she was a professor at Columbia Department of Biological Sciences. The Pe’er lab develops novel computational techniques to characterize gene regulation at the single-cell level, in...
Scientist Stories: Hans Waterham, The value of phenotypic assays in peroxisomal disorders
มุมมอง 353 หลายเดือนก่อน
Professor at Amsterdam University Medical Center. research.com/u/hans-r-waterham #biotechnology #science #vc #startup #startups #startupideas #biology #biotech #chemistry #business #speech #speeches #investing #investment #lifescience #casestudy #scientist #scientists #inventors #inventor #inventions #invention #research #innovation #siliconvalley #entrepreneur #entrepreneurship #entrepreneurs ...
Scientist Stories: Michael Rosenblum, Exploring Regulatory T-Cells
มุมมอง 443 หลายเดือนก่อน
Michael Rosenblum is a dermatologist who specializes in caring for patients with inflammatory and autoimmune skin diseases. One of the world's leading skin immunologists, Rosenblum's research has led to a better understanding of how immune responses are regulated in tissues. He also studies how to use this knowledge to develop better treatments for autoimmune disorders. After completing a docto...
Scientist Stories: Hannah Mitchison, Expanding Ciliopathies
มุมมอง 323 หลายเดือนก่อน
The Mitchison group’s aims are to understand the proteins responsible for building and maintaining ciliary functions in human health and disease. Current research is focussed on how different clinical outcomes for ciliopathy patients arise from different genetic mutations and on translating our lab research to the bedside by development of new genetic-based therapies. www.cilianetwork.org.uk/pe...
Scientist Stories: Leonardo Ferreira, Engineered Immune Cell Therapies
มุมมอง 1073 หลายเดือนก่อน
Leonardo M. R. Ferreira, Ph.D. is an Assistant Professor of Pharmacology and Immunology and, by courtesy, of Regenerative Medicine and Cell Biology at the Medical University of South Carolina and the Hollings Cancer Center. He holds a B.Sc. in biochemistry from University of Coimbra, Portugal, a Ph.D. in biochemistry from Harvard University, and completed a postdoctoral fellowship at the Univer...
Scientist Stories: Joel Zlotogora, Genetic carrier screening programs for reproductive purposes
มุมมอง 223 หลายเดือนก่อน
Joël Zlotogora, M.D., Ph.D., is an adjunct professor of human genetics at the Hebrew University Jerusalem. Joël Zlotogora is a pediatrician who has completed a fellowship in medical genetics and a Ph.D. in biochemical genetics in the genetic department in Haddasah Medical Center where he was a senior physician till 1999 when he moved to the Ministry of Health. Since 2000, Dr. Zlotogora is the D...
Scientist Stories: Laura Mackay, Memory T-Cell Responses
มุมมอง 1173 หลายเดือนก่อน
Laura Mackay is a Laboratory Head and Immunology Theme Leader at The Doherty Institute. Laura is a Howard Hughes Medical Institute (HHMI) and Bill & Melinda Gates International Scholar, a Dame Kate Campbell Fellow, a Sylvia & Charles Viertel Charitable Foundation Senior Medical Research Fellow, a National Health and Medical Research Council (NHMRC) Leadership Fellow, and in 2022 was the younges...
Scientist Stories: Nadav Ahituv, Characterization and Targeting of Gene Regulatory Elements
มุมมอง 903 หลายเดือนก่อน
The Ahituv lab is focused on identifying gene regulatory elements and linking nucleotide variation within them to various phenotypes including morphological differences between species, drug response and human disease. In addition, our lab is developing massively parallel reporter assays (MPRAs) that allow for high-throughput functional characterization of gene regulatory elements and the use o...
Scientist Stories: Shruti Naik, Epithelial Immunity
มุมมอง 723 หลายเดือนก่อน
Shruti Naik received her B.S. in Cell and Molecular Biology from the University of Maryland, College Park. After which she worked as research assistant at the Naval Medical Research Center studying traumatic injury and autoimmune onset. Shruti then matriculated into the University of Pennsylvania-National Institutes of Health Graduate Partnership Program and obtained her Ph.D. in Immunology und...
Scientist Stories: Anna-Katerina Hadjantonakis, Challenging Dogma in Stem Cells
มุมมอง 563 หลายเดือนก่อน
Research in the Hadjantonakis lab seeks to gain insights into the fundamental processes by which tissues and organs develop in their native context - the embryo - and consequently, how these mechanisms can be contextually recapitulated or adapted, in response to damage or in disease states. The lab are currently pursuing projects investigating mechanisms controlling cell identity and cell-cell ...
Scientist Stories: Raheleh Rahbari, Single-cell heterogeneity in the human brain
มุมมอง 313 หลายเดือนก่อน
Raheleh Rahbari is a Cancer Research UK Career Development Fellow, her research focuses on mutations acquired during ageing and how they can predispose to disease across generations. scholar.google.com/citations?user=MliFtigAAAAJ #biotechnology #science #vc #startup #startups #startupideas #biology #biotech #chemistry #business #speech #speeches #investing #investment #lifescience #casestudy #s...
Scientist Stories: John Marioni, Using Single Cell Genomics to Understand Cell Fate Decisions
มุมมอง 1033 หลายเดือนก่อน
Prior to the use of single cell based technologies, it was only possible to profile gene expression levels from bulk populations of millions of input cells. This assumes the cell population is homogeneous, which is clearly not the case, and there are many biological questions where bulk measures of gene expression are insufficient. During early development, for example, there are only a small n...
Scientist Stories: Jatinder Lamba, Pharmacogenomics saving lives with personalized treatment
มุมมอง 273 หลายเดือนก่อน
Scientist Stories: Jatinder Lamba, Pharmacogenomics saving lives with personalized treatment
Scientist Stories: Kasper Hansen, Computational analysis of DNA methylation in Disease
มุมมอง 303 หลายเดือนก่อน
Scientist Stories: Kasper Hansen, Computational analysis of DNA methylation in Disease
Scientist Stories: Karen Edelblum, Inflammatory Bowel Disease
มุมมอง 533 หลายเดือนก่อน
Scientist Stories: Karen Edelblum, Inflammatory Bowel Disease
Scientist Stories: Michelle Digman, In vivo Optical Imaging
มุมมอง 303 หลายเดือนก่อน
Scientist Stories: Michelle Digman, In vivo Optical Imaging
Scientist Stories: Philip Beales, Functional Genomics
มุมมอง 293 หลายเดือนก่อน
Scientist Stories: Philip Beales, Functional Genomics
Scientist Stories: Alfonso Martinez-Arias, On the Self-Engineering of Embryonic Stem Cells
มุมมอง 723 หลายเดือนก่อน
Scientist Stories: Alfonso Martinez-Arias, On the Self-Engineering of Embryonic Stem Cells
Scientist Stories: Marylyn Ritchie, Integrating Genomics Data
มุมมอง 423 หลายเดือนก่อน
Scientist Stories: Marylyn Ritchie, Integrating Genomics Data
Scientist Stories: Gwendalyn Randolph, Peritoneal Macrophages
มุมมอง 243 หลายเดือนก่อน
Scientist Stories: Gwendalyn Randolph, Peritoneal Macrophages
Scientist Stories: Cori Bargmann, Genes and Behaviors
มุมมอง 303 หลายเดือนก่อน
Scientist Stories: Cori Bargmann, Genes and Behaviors
Scientist Stories: Jan Hoeijmakers, The Aging Process
มุมมอง 1303 หลายเดือนก่อน
Scientist Stories: Jan Hoeijmakers, The Aging Process
Founder Stories: Michael Alonso, Immuno-Oncology Therapeutics
มุมมอง 303 หลายเดือนก่อน
Founder Stories: Michael Alonso, Immuno-Oncology Therapeutics
Scientist Stories: Amos Tanay, Genomic and Epigenomic Regulation at Multiple Scales
มุมมอง 553 หลายเดือนก่อน
Scientist Stories: Amos Tanay, Genomic and Epigenomic Regulation at Multiple Scales
Scientist Stories: Pavel Tolar, Genome-Wide CRISPR Cas9 Screening in Immune Cells
มุมมอง 393 หลายเดือนก่อน
Scientist Stories: Pavel Tolar, Genome-Wide CRISPR Cas9 Screening in Immune Cells
Scientist Stories: Julia Stingl, Pharmacogenetics From Bench to Drug Label
มุมมอง 593 หลายเดือนก่อน
Scientist Stories: Julia Stingl, Pharmacogenetics From Bench to Drug Label
Scientist Stories: Jolanda Van Leeuwen, Analysis of genetic interactions from yeast to human
มุมมอง 253 หลายเดือนก่อน
Scientist Stories: Jolanda Van Leeuwen, Analysis of genetic interactions from yeast to human

ความคิดเห็น

  • @shadow.banned
    @shadow.banned วันที่ผ่านมา

    How did Apple convince Steve Jobs not to get treatment? Was it Raytheon's MKULTA? He had a god complex at the end.

  • @GakhanAli
    @GakhanAli 7 วันที่ผ่านมา

    Good job

  • @GakhanAli
    @GakhanAli 7 วันที่ผ่านมา

    Good job

  • @jonetyson
    @jonetyson 9 วันที่ผ่านมา

    It is a shame that in the USA people hate pharma and biotech more than tobacco. Those industries are the only ones that can save us from the biggest problems facing humanity, which are heart disease, cancer, stroke, infectious disease, ect

  • @adamwhite7540
    @adamwhite7540 9 วันที่ผ่านมา

    Professor Xavier right thurr foolin nobody where u keepin the x-men ?

  • @TheBuckwoody
    @TheBuckwoody 13 วันที่ผ่านมา

    I missed it. Who asked this question and what was the answer? If you claim to be able to create a sperm and egg now through similar methodologies as in the creation of the ipc's, what DNA signature do they have? female (egg), male (sperm) ? XY Chromosome, Who's X, or Y chromosome signature will the sperm have? A Male would it have the XY chromosome of the individual, or his parents? The egg is it just the woman's/Individuals chromosome X, and which X, and if it is a female can you create a sperm cell from this process from a female, since she only has X chromosomes?

  • @michaelsweeney4547
    @michaelsweeney4547 15 วันที่ผ่านมา

    What was that first beta-blocker you mentioned?

  • @upgrade1015
    @upgrade1015 หลายเดือนก่อน

    She destroyed humanity and she doesn’t even realize it yet. What can be used for good can be used for bad and will be used for bad. Once you start making superhumans or humans with a little bit more of an advantage, this is the start of the end not to mention the bad guys who will now use weaponsto attack DNA… nano bots that will be able to affect DNA. This is bad. She has no idea how dark others can be. That’s the problem. Most people don’t realize how dark the controllers are….

  • @Someone-pc2im
    @Someone-pc2im หลายเดือนก่อน

    Thank you! For posting!!

  • @theyoten1613
    @theyoten1613 หลายเดือนก่อน

    I studied this paper in school :D. Very cool and Inspiring.

  • @Cleisthenes607
    @Cleisthenes607 หลายเดือนก่อน

    Thanks for the video.

  • @jorrek4756
    @jorrek4756 หลายเดือนก่อน

    😮

  • @Bandybear
    @Bandybear หลายเดือนก่อน

    There is no info in this video just this guys obvious concerns about gene editing and it’s a waste of time. Nobody wants these people doing this and releasing it into the environment

  • @Bandybear
    @Bandybear หลายเดือนก่อน

    Cancer is mostly environmental. I don’t care what anyone says. This is kind of ridiculous that our dna has mutations that cause cancer. If we are going on germ theory and evolution theory which is what they say theory. There is no way we could have evolved with all these mutations and problems without dying off. Our dna is in fact damaged but not naturally. This is crazy.they only get to have it one way though. We can’t believe everything we hear from doctors. But it’s gonna be like our junk dna that we have all this junk dna we don’t need. Such a small view of our vastly superior and complex human beings. We need to get that we don’t know everything about the body for sure. But we act as if we are sure. That seems like a bad idea to keep letting people destroy us from chemicals and toxic water and food. Maybe woman would be more likely to get pregnant if they hadn’t been poisoned their entire life through nasty institutions. Nothing is free , make no mistake we will pay

  • @RParkinson
    @RParkinson หลายเดือนก่อน

    great episode!

  • @josealvarez9237
    @josealvarez9237 หลายเดือนก่อน

    In some clinical trials, the patient participants is something to be used for the benefit of the sponsors with no regard at all for the participants anymore than if they were mice.

  • @josealvarez9237
    @josealvarez9237 หลายเดือนก่อน

    The more we learn about NK cells the easier will be to prevent cancer.

  • @josealvarez9237
    @josealvarez9237 หลายเดือนก่อน

    Some doctors still have to learn that NK cells are lymphocytes and that the lymphocytes are the three pillars of the immune system.

  • @josealvarez9237
    @josealvarez9237 หลายเดือนก่อน

    Before all that can happen, doctors have to turn the corner and leave behind the idea that to kill the cancer you also have to kill the immune system and the microbiome.

  • @josealvarez9237
    @josealvarez9237 หลายเดือนก่อน

    Not only we will have off-the shelf NK cell, we will have a tool like AlphaFold 3 to inspect and analyse a million NK cells in minutes.

  • @josealvarez9237
    @josealvarez9237 หลายเดือนก่อน

    We will soon have NK cells mediated cure of cancer.

  • @Darkblade123-n4l
    @Darkblade123-n4l หลายเดือนก่อน

    C2h15o4+nacl=c3+h15na+o4cl

  • @bbarsher
    @bbarsher หลายเดือนก่อน

    in the midst of a bio-tech Renaissance

  • @bluedaffodil2023
    @bluedaffodil2023 2 หลายเดือนก่อน

    So amazing! I love how she said “There’s the right way, there’s the wrong way, and there’s Cynthia’s way”. This scientist inspires me so so much

  • @themrvims
    @themrvims 2 หลายเดือนก่อน

    One of the top 100 scientific talks.

  • @bluedaffodil2023
    @bluedaffodil2023 2 หลายเดือนก่อน

    She's so cool!

  • @CastorMacadat
    @CastorMacadat 2 หลายเดือนก่อน

    Scandal polmobey

  • @donaldlloyd4071
    @donaldlloyd4071 2 หลายเดือนก่อน

    Swell, some dickhead just said that he was my son. WTF ?

  • @DT-Mainnet
    @DT-Mainnet 2 หลายเดือนก่อน

    Interview with criminal Killers...

  • @ulrichgerhardosterloh6069
    @ulrichgerhardosterloh6069 2 หลายเดือนก่อน

    Interesting but microphones used could have been better and should be for such subjects

  • @LeonardoKoomen
    @LeonardoKoomen 2 หลายเดือนก่อน

    Amazing Channel. Thank you for posting these.

  • @BrittHarms
    @BrittHarms 2 หลายเดือนก่อน

    Any advice to help me quit smoking? Thanks.

  • @thedude6405
    @thedude6405 2 หลายเดือนก่อน

    I like this speech, easy to understand even for me dumb dumb.

  • @РодионЧаускин
    @РодионЧаускин 2 หลายเดือนก่อน

    Martinez Cynthia Martin Deborah Rodriguez Frank

  • @newyorksilverking9394
    @newyorksilverking9394 3 หลายเดือนก่อน

    Stock down 70 % since video aired last year...Just signed biggest deal in history of company with Bristol Meyer and the stock tanked even further..You gotta be nuts investing in these little biotech micro cap stocks..

  • @bishopscore
    @bishopscore 3 หลายเดือนก่อน

    There are more views on videos about silly tik tok trends than life changing scientific bteakthroughs. Glad i am not with the masses.

  • @sapelesteve
    @sapelesteve 3 หลายเดือนก่อน

    Just finished reading Dr. Cech's book "The Catlayst". Terrific read for anyone interested in learning about the workings of RNA! 👍👍

  • @niamcd6604
    @niamcd6604 3 หลายเดือนก่อน

    She killed herself and absolutely nothing changed in the meantime. Universities push out minorities, keep women as little as possible in the academia and prevent them from achieving tenure in STEM. As much as the thought of this may seem 'nice', in reality it's just advertising to whitewash their own wrongdoings. Universities stress you out on purpose, they push working class students put so to keep nepotism in place and keep their white NEO-NAZIS in position of power. Besides, as much as I honestly admired Dr Lander, the truth is has abused many colleagues to the point of having a mental breakdown. So in the words of a frustrated neuroscience postgrad, WTF is all this??? And most importantly, WHO TF is this for. A young student, a young woman died, yet again cause stress bullying and humiliation are the pillars of the academia.

  • @SpenderDebby-x6n
    @SpenderDebby-x6n 3 หลายเดือนก่อน

    Harris Anna Thompson Margaret Anderson Barbara

  • @TimothyThompson-t9h
    @TimothyThompson-t9h 3 หลายเดือนก่อน

    Lizeth Neck

  • @BestFitSquareChannel
    @BestFitSquareChannel 3 หลายเดือนก่อน

    🌞🖖🏼

  • @BestFitSquareChannel
    @BestFitSquareChannel 3 หลายเดือนก่อน

    Mind blown! If I see Dr. Li, Dr. Hassabis alone I’m viewing. Together!? I almost passed out. 🌞🤸🏽‍♂️🫶🏼🖖🏼

  • @zachary_thomas
    @zachary_thomas 3 หลายเดือนก่อน

    Thanks! What did she mean at 30:00 that the apps don't need to be HIPPA compliant?

  • @AlfredStrehli-q3o
    @AlfredStrehli-q3o 3 หลายเดือนก่อน

    This is truly cosmic in implication . And ethics is obviously church''s concern!

  • @jesse_kihara
    @jesse_kihara 3 หลายเดือนก่อน

    Carl might win a Nobel in near future

  • @jesse_kihara
    @jesse_kihara 3 หลายเดือนก่อน

    Great

  • @alz123alz
    @alz123alz 3 หลายเดือนก่อน

    DR. RON VALE DESERVES SEVERAL NOBEL PRIZES

  • @bpath60
    @bpath60 3 หลายเดือนก่อน

    From Bench to bedsideThank you

  • @sunnypanday
    @sunnypanday 3 หลายเดือนก่อน

    00:04 Anima Anandkumar's journey in AI Revolution 02:31 Transition from matrices to tensors in generative AI and its impact 07:40 Use of generative AI in modeling protein-ligand binding 10:17 Using large scale biological language model for genome level understanding 15:07 Generative AI and LLMs are key for understanding DNA encoding and evolutionary gaps 17:32 Utilizing generative AI for accelerating scientific discoveries 21:49 Generative AI can model complex phenomena like fluid dynamics and seismic waves. 24:06 Neural operators allow flexibility in resolution for scientific simulations 28:38 Combining traditional and nonlinear transforms for universal function approximation 30:56 Using neural operator frameworks to improve weather forecasting 35:20 Neural operator-based methods bring speed and accuracy to various scientific applications 37:37 Collaboration with domain scientists and industry is crucial for advancing AI in science 41:54 Generative AI as seed model for model fine-tuning 44:10 AI-based methods enable quicker computations through better nonlinear transformations 48:45 Using AI to improve weather prediction models 51:01 AI models enable running thousands of Ensemble members cheaply for better weather predictions. 55:22 Advances in generative AI for decision making in open-world settings 57:37 Generative AI in Minecraft is about unleashing creativity and solving open-ended tasks 1:01:57 Foundation models for decision making 1:04:03 Anima Anandkumar talks about her work

  • @InquilineKea
    @InquilineKea 3 หลายเดือนก่อน

    I met him in lund!!